Phase-contrast microscopic image of Vero cells. Vero cells are a lineage of cells used in cell cultures. The lineage was developed on 27 March 1962, by Yasumura and Kawakita at the Chiba University in Chiba, Japan. The vero cell line pdf cell line was named “Vero” after an abbreviation of verda reno, which means “green kidney” in Esperanto, while vero itself means “truth” in Esperanto.
The Vero cell lineage is continuous and aneuploid. A continuous cell lineage can be replicated through many cycles of division and not become senescent. Aneuploidy is the characteristic of having an abnormal number of chromosomes.
The whole genome sequence of a Vero cell line was determined by Japanese investigators in 2014. 9-Mb deletion, causing the loss of the type I interferon gene cluster and cyclin-dependent kinase inhibitors CDKN2A and CDKN2B in the genome.